Selene must fend off brutal attacks from both the Lycan clan and the vampire faction that betrayed her. Joining forces with David and Thomas, he embarks on a quest to end the eternal war between the two races, even if it means making the ultimate sacrifice.
In the years since she and her human-lycanthrope lover, Michael, defeated Elder Marcus, vampire warrior Selene has been captured by the humans, as they wage an all-out war against the lycans and vampires. Waking up after more than a decade, Selene discovers that Michael is dead, but has given birth to their daughter, Eve. Shunned by almost all but one of the surviving vampires, even Selene seems powerless against her latest opponent: a genetically enhanced lycanthrope.
Viktor, the cruel king of the vampires, has hunted the werewolves for centuries. The young Lycan Lucian rallies his people against Viktor and his Death Dealer warriors. With his secret lover Sonja, a vampire, by his side, Lucian leads the werewolves in a final battle to break free from bondage or die trying.
Selene and the Werewolf Michael love each other, but are loathed by members of their own clans. Marcus, an ancient creature obsessed with perpetuating war between them, hounds them for clues that may provide a key to bridging the gap between their species. Continually harassed by enemies on both sides, the lovers explore their past as they search for their destiny.
Under cover of night, the vampires engage in an ancient battle with their sworn enemies, the lycans, a clan of violent werewolves. Selene, a vampire orphaned by a bloody Lycan attack, works for the vampire clan as a trained assassin. When the lycans take a mysterious interest in Michael Corvin, an exceptional mortal doctor, Selene fights to save him from Lucian, a ruthless lycan leader bent on ending the bloodline of vampires.